B3842 - Creating ALSPAC polygenic indexes for the SSGAC Polygenic Index Repository - 16/09/2021

B number: 
B3842
Principal applicant name: 
Tim Morris | University of Bristol (United Kingdom)
Co-applicants: 
Dr Aysu Okbay, Professor Daniel Benjmain, Dr Alexander Young, Hariharan Jayashankar, Seyed Moeen Nehzati, Tanner Bangerter , Jonathan Jala
Title of project: 
Creating ALSPAC polygenic indexes for the SSGAC Polygenic Index Repository
Proposal summary: 

In this project we will create "polygenic indexes" for the ALSPAC participants. Polygenic indexes are summaries of a persons known genetic predisposition to a particular trait, such as height. We will create these indexes for up to 47 different traits, which can then be use by other researchers.

Impact of research: 
Wide use by other researchers in research projects.
Date proposal received: 
Friday, 13 August, 2021
Date proposal approved: 
Monday, 13 September, 2021
Keywords: 
Genetics, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Mental health, Obesity, GWAS, Statistical methods, Genetics, Genomics