B3631 - The relationship of adverse pregnancy and perinatal outcomes with blood NMR metabolites in the offspring - 09/10/2020

B number: 
B3631
Principal applicant name: 
Ahmed Elhakeem | MRC IEU
Co-applicants: 
Deborah Lawlor
Title of project: 
The relationship of adverse pregnancy and perinatal outcomes with blood NMR metabolites in the offspring
Proposal summary: 

The aim of this study is to explore associations of common adverse pregnancy and perinatal outcomes with offspring plasma/serum-based NMR metabolites and compare associations between those conditions that might result in / reflect fetal undernutrition with those resulting in / reflecting fetal overgrowth. We will also assess whether associations differ by age at NMR measurement in the offspring.

Impact of research: 
Knowledge advancement
Date proposal received: 
Thursday, 8 October, 2020
Date proposal approved: 
Friday, 9 October, 2020
Keywords: 
Epidemiology, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Metabolomics, Cardiovascular