B3431 - Association of Maternal education with DNA-methylation - 16/12/2019

B number: 
B3431
Principal applicant name: 
Giulia Mancano | IEU
Co-applicants: 
Dr Gemma Sharp
Title of project: 
Association of Maternal education with DNA-methylation
Proposal summary: 

Maternal education, a predictor of social-economic status, has been associated with several offspring health outcomes during the life course (e.g. obesity, type 2 diabetes, cognitive function...). The biological mechanisms regulating this association are yet to be understood. Possible mediation in the maternal education-offspring health outcome relationship might be played by DNA-methylation epigenetics markers. We therefore aim to investigate how epigenetics changes are associated to maternal educational attainment.

Impact of research: 
Produce evidence in support or against the association between DNA-methylation and maternal education
Date proposal received: 
Thursday, 12 December, 2019
Date proposal approved: 
Monday, 16 December, 2019
Keywords: 
Epigenetics, Microarrays, Maternal educational attainment